What’s emerging
- Next-gen CAR-T and CAR-NK
- Allogeneic (“off-the-shelf”) cell therapies
- Engineered immune and stem cells
Why it’s promising
- Clinical validation already exists
- Engineering improvements drive each generation
IP significance
- Claims often hinge on cell type, modification method, and functional phenotype
- Manufacturing and persistence claims are increasingly valuable
- Enablement and written description are frequent pressure points
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