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Novel zinc finger fusion proteins for nucleobase editing
Publication Number: US 20250361528 A1Filing Date: December 22, 2022Publication Date: November 27, 2025Applicant/Assignee: Sangamo Therapeutics, Inc.Inventors: Friedrich A. Fauser, Jeffrey C. Miller, Sebastian Arangundy What This Patent Covers This patent application describes advanced base editor systems that combine Sangamo’s proprietary zinc finger protein (ZFP)…
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Methods and Compositions for CRISPR/Cas9-Mediated Huntingtin Gene Editing
What It Covers This patent application discloses CRISPR/Cas9 gene editing constructs and associated methods for targeting and modifying the huntingtin gene (HTT) — a key mutation responsible for Huntington’s disease — with the goal of…
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Melanocortin Subtype‑2 Receptor (MC2R) Antagonists and Uses Thereof
Assignee: Crinetics Pharmaceuticals, Inc.Patent Number: 12,479,825 B2Filed: October 30, 2020 (priority from earlier filings)Issued: November 25, 2025Inventors: Sangdon Han, Sun Hee Kim, Yunfei ZhuPatent Classification: Medicinal Chemistry / GPCR Modulators What This Patent Covers This patent…
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