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A general genome editing strategy using CRISPR lipid nanoparticle spherical nucleic acids
Published in PNAS (September 5, 2025) — a major advance in gene-editing delivery technology by Zhenyu Han, Chi Huang, Taokun Luo, Chad A. Mirkin, and colleagues. What the study covers This PNAS paper reports the…
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The Use of CD40 Inhibitors for Inhibiting an Immune Response and Enabling Immunogen Administration and Re‑Administration
Patent Title: The Use of CD40 Inhibitors for Inhibiting an Immune Response and Enabling Immunogen Administration and Re‑AdministrationPublication Number: WO/2025/184603Application Number: PCT/US2025/017984Filing Date: February 28, 2025Publication Date: September 4, 2025Applicant: Regeneron Pharmaceuticals, Inc. (Tarrytown, NY,…
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Compositions and Methods for Angiopoietin‑Like 3 (ANGPTL3) Editing
Application Number: PCT/US2025/017864Filing Date: February 28, 2025Publication Number: WO/2025/184520Publication Date: September 4, 2025Applicant: Intellia Therapeutics, Inc. (Cambridge, MA, USA)Inventors: Gamze Karaca, Trisha Das, Arti Kanjolia, et al. What This Patent Covers This international patent application discloses genome‑editing compositions and methods directed at the…
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