A world of possibilities
Navigating life sciences and medtech to the extraordinary—driven by creativity, curiosity, and the courage to build a fulfilling journey.
-
Cell subtype‑specific effects of genetic variation in the Alzheimer’s disease brain
Journal: Nature Genetics Published: 21 March 2024 DOI: 10.1038/s41588‑024‑01685‑y Authors: Masashi Fujita, Zongmei Gao, Lu Zeng, Cristin McCabe, Charles C. White, Bernard Ng, et al. What This Covers This research used single‑nucleus RNA sequencing of ~1.5 million individual brain…
-
Small-molecule inhibitor of the JAK family of kinases
Assignee: Janssen Pharmaceutica NV (a Johnson & Johnson subsidiary)Inventors: Edward F. Attiyeh, Kurtis E. Bachman, Gerald C. Chu, Tatiana Koudriakova, David C. Polidori, Gary V. BorzilloFiled: March 9, 2022Patent Granted: August 19, 2025Publication Number: US20220288041…
-
Brainwide silencing of prion protein by AAV‑mediated delivery of an engineered compact epigenetic editor
Journal: Science Publication Date: June 28, 2024 DOI: 10.1126/science.ado7082 Lead Authors: Edwin N. Neumann, Tessa M. Bertozzi, Elaine Wu, et al. Institutions: Broad Institute of MIT and Harvard, Whitehead Institute, MIT, and collaborators. What This Paper Covers This study reports the development and…
