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Highly accurate protein structure prediction with AlphaFold
Jumper et al. (2021) Published in: Nature 596, 583–589 (July–August 2021)DOI: 10.1038/s41586‑021‑03819‑2This paper reported a major breakthrough in computational structural biology: a deep‑learning system capable of accurately predicting three‑dimensional protein structures from amino acid sequences.…
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Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice
Chen Yanpu et al. (2021) Published in: Science 373(6562):1537–1540 (September 24, 2021)DOI: 10.1126/science.abg5159 What This Study Found This study demonstrated a novel cellular reprogramming approach that enables damaged adult heart muscle cells (cardiomyocytes) to revert…
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Evaluating the Analytical Validity of Circulating Tumor DNA (ctDNA) Sequencing Assays for Precision Oncology
Published: Nature Biotechnology 39(9):1115–1128 (2021)DOI: 10.1038/s41587‑021‑00857‑zAuthors: Ira W. Deveson, Binsheng Gong, Kevin Lai, et al. What This Paper Covers This study conducted a rigorous, multi‑site, cross‑platform evaluation of circulating tumor DNA (ctDNA) sequencing assays, which are…
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