A world of possibilities
Navigating life sciences and medtech to the extraordinary—driven by creativity, curiosity, and the courage to build a fulfilling journey.
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CAR-T 2.0: off-the-shelf cells vs CAR-NK
CAR-T 2.0 refers to improvements over first-generation CAR-T therapies, which are autologous (patient-derived), personalized, and require long manufacturing timelines. Next-gen CAR-T aims to: Reduce manufacturing time Increase accessibility Improve safety and persistence Expand applicability to…
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In Vivo Gene Delivery
In vivo gene delivery refers to introducing genetic material directly into a living organism’s cells, rather than manipulating cells outside the body (ex vivo), to achieve therapeutic gene expression in target tissues for disease treatment,…
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Base Editing vs Prime Editing vs Epigenetic Editing
1. Base Editing Core mechanism: Combines a CRISPR-Cas nickase (or dead Cas) with a nucleotide-modifying enzyme, usually a cytidine or adenine deaminase Directly converts one base to another without making a double-strand DNA break Uses…
