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Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial
What This Covers This Nature Medicine study reports the results of a first‑in‑human phase 1/2 clinical trial combining a personalized neoantigen vaccine with the immune checkpoint inhibitor pembrolizumab in patients with advanced hepatocellular carcinoma (HCC) —…
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Combination therapy using glucose-dependent insulinotropic polypeptide receptor antagonist compounds and GLP-1 receptor agonist peptides
What It Covers This international patent application discloses combination therapies that pair: Key elements include: 1. Combination therapeutic compositions:The application claims pharmaceutical formulations that include specific GIP receptor antagonist compounds together with GLP-1 receptor agonist…
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Conjugates Comprising Transferrin Receptor Binding Protein
Patent Application (International / PCT): PCT/US2025/013955Publication Number: WO/2025/166111Filing Date: January 31, 2025Publication Date: August 7, 2025Applicant / Assignee: Eli Lilly and CompanyInventors (examples): Riazul Alam, Guillermo S. Cortez, Yan Wang (et al.) What This Patent…
BioTech IP Review 